Search results for "Matrix-assisted laser desorption electrospray ionization"

showing 7 items of 7 documents

A new interface to couple thin-layer chromatography with laser desorption/atmospheric pressure chemical ionization mass spectrometry for plate scanni…

2005

An interface to allow on-line qualitative and quantitative full-plate detection and analysis of compounds separated by thin-layer chromatography (TLC) is presented. A continuous wave diode laser is employed as a desorption source. Atmospheric pressure chemical ionization mass spectrometry ionizes and subsequently identifies the desorbed sample molecules. Besides direct laser desorption on untreated TLC plates, graphite particles were used as a matrix to couple in the laser power and improve the efficiency of desorption.

Desorption electrospray ionizationChromatographyMatrix-assisted laser desorption electrospray ionizationChemistryOrganic ChemistryAnalytical chemistryEquipment DesignMass spectrometryIon sourceSoft laser desorptionAnalytical ChemistryAtmospheric-pressure laser ionizationSpecimen HandlingEquipment Failure AnalysisSystems IntegrationAtmospheric PressureSpectrometry Mass Matrix-Assisted Laser Desorption-IonizationDirect electron ionization liquid chromatography–mass spectrometry interfaceSpectroscopyAmbient ionizationRapid communications in mass spectrometry : RCM
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Production of negative osmium ions by laser desorption and ionization.

2010

The interest to produce negative osmium ions is manifold in the realm of high-accuracy ion trap experiments: high-resolution nearly Doppler-free laser spectroscopy, antihydrogen formation in its ground state, and contributions to neutrino mass spectrometry. Production of these ions is generally accomplished by sputtering an Os sample with Cs(+) ions at tens of keV. Though this is a well-established method commonly used at accelerators, these kind of sources are quite demanding and tricky to operate. Therefore, the development of a more straightforward and cost effective production scheme will be of benefit for ion trap and other experiments. Such a scheme makes use of desorption and ionizat…

Matrix-assisted laser desorption electrospray ionizationMaterials scienceThermal ionizationMass spectrometryIon sourceSoft laser desorptionlaw.inventionAtmospheric-pressure laser ionizationPhysics::Plasma PhysicsReflectronlawPhysics::Atomic and Molecular ClustersPhysics::Atomic PhysicsAtomic physicsInstrumentationAmbient ionizationThe Review of scientific instruments
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A laser ion source for trace analysis

1988

A laser ion source has been set up which is based on resonant stepwise excitation and ionization of atomic vapor confined in an ionization chamber. Using a pulsed copper vapor/dye laser system with a high repetition rate (6.5 kHz) one expects high efficiency and high selectivity for this new type of ion source. First test experiments with lead are reported.

Matrix-assisted laser desorption electrospray ionizationChemistryClinical BiochemistryAnalytical chemistryGeneral MedicineBiochemistryIon sourceAnalytical ChemistryAtmospheric-pressure laser ionizationIon beam depositionIonizationGeneral Materials SciencePhysics::Atomic PhysicsAtomic vapor laser isotope separationElectron ionizationAmbient ionizationFresenius Zeitschrift f�r Analytische Chemie
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Selective laser ionization of radioactive Ni-isotopes

1997

Abstract A chemically selective laser ion source based on resonance ionization of atoms in a hot cavity has been applied in the study of Ni-isotopes at the CERN-ISOLDE on-line isotope separator. Laser ionization enhanced the yields of long-lived Ni-isotopes almost four orders of magnitude when compared to the yields obtained with the surface ionization mode of the source. As a result, high yields of long-lived Ni-isotopes were obtained. Separation efficiencies of 0.3 and 0.8% were obtained for Ni produced in uranium-carbide, produced from uranium-di-pthalocyanine, and Ta-foil targets, respectively. Ni was found to be released very slowly from the present target and ion source combination.

Nuclear and High Energy PhysicsChemical ionizationMatrix-assisted laser desorption electrospray ionizationChemistryRadiochemistryAnalytical chemistryThermal ionizationIon sourceAtmospheric-pressure laser ionizationIonizationPhysics::Atomic PhysicsNuclear ExperimentInstrumentationElectron ionizationAmbient ionizationNuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms
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Measurement of nanoparticle mass distributions by laser desorption/ionization time-of-flight mass spectrometry.

2011

In this paper, access to the mass distribution analysis of nanoparticles is described based on laser desorption/ionization and time of flight mass spectrometry. Two examples are given, demonstrating the accurate mass distribution analysis of nanoparticles fabricated both ex situ and in situ during the laser-assisted desorption process. The potentials and the limitations of the method are discussed, with special emphasis on carbonaceous clusters and molecules.

Desorption electrospray ionizationStatic secondary-ion mass spectrometryMatrix-assisted laser desorption electrospray ionizationChemistryAnalytical chemistryGeneral Materials ScienceTime-of-flight mass spectrometryCondensed Matter PhysicsMass spectrometrySoft laser desorptionIon sourceAmbient ionizationJournal of physics. Condensed matter : an Institute of Physics journal
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Laser preparation of bunched ion beams

1997

Abstract Laser ionization at ISOLDE is performed with high repetition laser beams in the ion source unit and for daughter elements with low repetition lasers synchronized with laser desorption from a secondary target. We are preparing an implementation of thermal adsorption followed by laser desorption and laser ionization in the target ion source unit of ISOLDE. The combination of resonance ionization with thermal bunching allows the preparation of bunched and chemically pure ion beams. Bunched ion beams of Mg or Ca are prepared for post-acceleration at REX-ISOLDE. In order to investigate the process of adsorption and pulsed laser desorption, experiments are performed with Ba vapour. In a …

Nuclear and High Energy PhysicsDye laserMatrix-assisted laser desorption electrospray ionizationChemistryAnalytical chemistryPhysics::OpticsLaserSoft laser desorptionIon sourcelaw.inventionAtmospheric-pressure laser ionizationX-ray laserlawIonizationPhysics::Atomic and Molecular ClustersPhysics::Accelerator PhysicsPhysics::Atomic PhysicsAtomic physicsInstrumentationNuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms
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Multi-color resonance ionization of laser ablated gadolinium at high laser power

2005

Abstract Spectroscopic and analytical properties of a trace analytical method using multi-step resonance ionization at high laser intensities (>kW/cm 2 ) have been investigated with gadolinium as a test element. Strongly saturated transitions are observed, which have been used for a temperature determination of the atoms in the laser ablated plume. Regimes of multi-step resonance ionization and multiphoton ionization could be distinguished. Analytical performances due to resonance enhancement and resulting discrimination against non-resonant background, precision in isotope ratio determination and overall detection efficiency are discussed.

Materials scienceMatrix-assisted laser desorption electrospray ionizationLaser ablationPhotoionizationLaserAtomic and Molecular Physics and OpticsIon sourceElectronic Optical and Magnetic Materialslaw.inventionAtmospheric-pressure laser ionizationlawIonizationPhysics::Atomic and Molecular ClustersPhysics::Atomic PhysicsLaser power scalingElectrical and Electronic EngineeringPhysical and Theoretical ChemistryAtomic physicsOptics Communications
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